Upgrading the DNA Sequence of the Rat Genome
نویسندگان
چکیده
The Brown Norway or laboratory rat (Rattus norvegicus) genome was sequenced in a project jointly supported by the NHGRI and the NHLBI (12). This was the third mammalian project undertaken by the NIH but the first that would only be taken to the draft stage. The project was a complex collaboration led by the BCM-HGSC (BAC skims, wgs, assembly, annotation, overall coordination) and including Celera Genomics Inc. (wgs reads), Genome Therapeutics Inc. (wgs reads, Y chromosome), University of Utah (wgs reads), TIGR (BAC end sequences), British Columbia Genome Sciences Centre (BAC fpc map), NISC-NHGRI (BAC sequencing), Washington University Genome Sequencing Center (BAC fpc map), and Children’s Hospital Oakland Research Institute (BAC libraries). Annotation and analysis was performed by an international consortium of over 70 analysts.
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